Department of Cell Biology
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December 6, 2020

 teaserrico_review2020-130x100In this review, Rico and coauthors discuss the complex interplay between RNA-binding proteins (RBPs) in developing and mature neurons. These complex networks are crucial for important regulatory pathways controlling all aspects of brain homeostasis including neurogenesis, synaptic transmission and synaptic plasticity. Therefore, imbalances in RBP homeostasis cause neurological and neuropsychiatric diseases such as epilepsy and autism spectrum disorders.

Picture courtesy Shalev Itzkovitz, Michael Kiebler, Debby Silver and Edgar Gomes laboratories

 

 

RicoPhysRev2020Graphical abstract_final_1