Dorothee Dormann

Selected publications

Hofweber M*, Hutten S*, Bourgeois B, Spreitzer E, Niedner-Boblenz A, Schifferer M, Ruepp MD, Simons M, Niessing D, Madl T, Dormann D (2018). Phase separation of FUS is suppressed by its nuclear import receptor and arginine methylation. Cell, 173(3):706-719.e13

Ederle H, Funk C, Abou-Ajram C, Hutten S, Funk EBE, Kehlenbach R, Bailer S, Dormann D (2018). Nuclear egress of TDP-43 and FUS occurs independently of Exportin-1/CRM1, Scientific Reports, 8(1):7084.

Ederle H, Dormann D (2017). TDP-43 and FUS – en route from the nucleus to the cytoplasm.
FEBS Letters, 591(11):1489-1507

Khosravi B, Hartmann H, May S, Möhl C, Ederle H, Michaelsen M, Schludi MH, Dormann D, Edbauer D (2017). Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD. Hum Mol Genet. 26(4):790-800

Bowden HA, Dormann D (2016). Altered mRNP granule dynamics in FTLD pathogenesis. J Neurochem. 138 Suppl 1:112-33.

Suárez-Calvet M, Neumann M, Arzberger T, Abou-Ajram C, Funk E, Hartmann H, Edbauer D, Kremmer E, Göbl C, Resch M, Bourgeois B, Madl T, Reber S, Jutzi D, Ruepp MD, Mackenzie IR, Ansorge O, Dormann D*, Haass C* (2016). Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS. Acta Neuropathol. 131(4):587-604.

Bentmann E, Haass C, Dormann D (2013). Stress granules in neurodegeneration – lessons learnt from FUS and TDP-43. FEBS J. 280(18):4348-70

Dormann D, Madl T, Valori C, Bentmann E, Tahirovic S, Abou-Ajram C, Kremmer E, Ansorge O, Mackenzie IR, Neumann M, Haass C (2012). Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS. EMBO J. 31(22):4258-75

Bentmann E, Neumann M, Tahirovic S, Rodde R, Dormann D*, Haass C* (2012). Requirements for stress granule recruitment of Fused in sarcoma (FUS) and TAR DNA-binding protein of 43 kDa (TDP-43). J Biol Chem. 287(27):23079-94

Dormann D, Haass C (2011). TDP-43 and FUS – A nuclear affair. Trends Neurosci. 34(7) pp. 339-348

Dormann D, Rodde R, Edbauer D, Bentmann E, Fischer I, Hruscha A, Than M, Mackenzie I, Capell A, Schmid B, Neumann M, Haass C. (2010) ALS-associated FUS mutations disrupt Transportin-mediated nuclear transport. EMBO J. 29(16):2841-57

Dormann D, Capell A, Carlson AM, Shankaran SS, Rodde R, Neumann M, Kremmer E, Matsuwaki T, Yamanouchi K, Nishihara M, Haass C. (2009) Proteolytic processing of TAR DNA Binding Protein-43 by caspases produces C-terminal fragments with disease defining properties independent of progranulin. J Neurochem. 110(3):1082-94

Schmid D, Pypaert M, Münz C. (2007) MHC class II antigen loading compartments continuously receive input from autophagosomes. Immunity 26(1):79-92

Paludan C*, Schmid D*, Landthaler M, Vockerodt M, Kube D, Tuschl T, Münz C. (2005) Endogenous MHC class II processing of a viral nuclear antigen after autophagy. Science 307(5709):593-6

Note: Since 2007 Schmid D = Dormann D